Fitzalan House Veterinary Group was established almost 100 years ago, well before it acquired it's current name. The original horse and farm-orientated practice was based in Arundel, and served all the farm and domestic animals in the surrounding area.  Mr Angwin, the then Principal, commuted over from Brighton every day and carried out farm calls with his horse and cart. He was succeeded in 1926 by a Canadian Cavalry Officer, Mr. Hill, who presided over the young practice and set up a branch in Littlehampton in 1946. He was joined by Olaf Swarbrick, who later became a partner and renowned poultry expert, in 1950. In 1951 the practice was taken over by Mike Ashton. Ian Hutchinson joined the partnership in 1966.

In 1970 this farm-based practice decided that with the increasing specialisation and depth of knowledge evolving within the veterinary field, the community would be best served by specialist branches of the original practice. It therefore split into Equine, Farm and Small Animal components. Mike Ashton retained the Equine side, later to become Tortington Equine Clinic, and Ian Hutchinson assumed control of the Farm work.

The Small Animal Practice flourished in Mr. Skelton's hands and in 1974 Bill set up a branch practice at Church Hill in  Angmering (where it is still situated today).  In 1977 the Littlehampton branch moved to it's current site in Fitzalan Road and it was then that it acquired it's current name, Fitzalan House Veterinary Group. In 1979 the Arundel branch moved to River Road.

John Wooton had established a Veterinary Clinic in East Preston from scratch in 1962.  In 1984 Bill Skelton acquired this clinic, which at that time was located in Sea lane, in a converted stable block. The East Preston Surgery relocated in February 2003 to it's current site beside the Library in The Street.

Michael Kingsbury joined Bill Skelton as an assistant in 1988 and then became Bill's partner in 1993.  On Bill's retirement in 2002 he became sole principal.